As previously discussed, because of the volume of water actually tested (.1ml for endotoxins vs. 100ml for WFI), the microbiological test offers a good index of the level of contamination in a system.
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Dec 16, 2015 · dead volume and a sure, tight connection. Poorly connected flow path fittings are one of the top reasons for peak tailing, peak broadening, split peaks, and carryover. That’s because dead volume or micro-leakage can cause extra-column volume, which hinders the performance and reproducibility of HPLC and UHPLC.
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It is a high molecular weight polyolefin material. Like all another polyolefin low-density polyethylene is also non-toxic, non-contaminating and high quality of break resistance. It is lighter than water, chemically inert and insolvent at room temperatures.
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Monitoring and Validation of High Purity Water Systems with the LAL test for pyrogens, T.J. Novistsky, Pharmaceutical Engineering, March-April, 1984. [ Previous Chapter ] [ Table of Contents
